Photo Cross Linkers

Photo cross linkers are a helpful tool for the investigation of peptide-protein interactions.

Irradiation by UV-light creates a stable covalent bond between the interaction partners, which facilitates conclusions regarding the mode of interaction.

Benzoyl-phenylalanine (Bpa) can be incorporated as a building block at any position of the peptide. DMNB can be attached to any amino or mercapto group of the peptide.

Amino acids with a diazirinyl moiety can be used as photo cross linkers as well. BIOSYNTAN offers the incorporation of so called 'photo leucine' or 'photo methionine' at any position of the peptide.