The small protein ubiquitin plays an important role in a variety of cell processes, e.g. in degradation of misfolded proteins, in signal transduction, and regulation of transcription. For all of these reasons, there has been increased research focused on ubiquitin.
Fluorescently labeled variants of ubiquitin are particularly interesting for localization studies. Rhodamine 110 derivatives are suitable tools for the investigation of deubiquitinating enzymes. Different modification at the C-terminus complete the portfolio of BIOSYNTAN: